Shri Vile Parle Kelvani Mandal's

  C. B. Patel Research Centre
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  • Recognized as SIRO by the Department of Scientific and industrial Research, Ministry of science and Technology, Government of India.
  • Approved by Drug Controller General (DCGI), Government of India for undertaking Bioavailability / Bioequivalence studies for new drugs and formulations. The Centre has completed several such studies on drugs/formulations for submission to DCGI and for export.
  • The Research Centre has been accorded accreditation by the Department of Indian System of Medicine and Homeopathy, Ministry of Health, Government of India to carry out Research and Development work on traditional medicine.
  • MOU’s with two international companies
  • Two patent on the process of extraction of active ingredient from herbs.
  • Recognized as Post-Graduate Centre by the University of Mumbai for admitting students for M. Sc. / Ph.D. programme.
    No. of students successfully completing a) M. Sc. (By Research) : 2
    b) Ph.D. : 9
  • Total number of research papers :
    a) Communicated / Published - 40
    c) Presented at national and international conference – 28.
  • Thalassaemia Diagnostic Unit established for screening and counselling students as a service to the community.
  • Established facilities for vocational training in Industrial and Analytical chemistry, Medical Laboratory Technology, Biotechnology and Food Technology.
  • Approved under Section 35(1)(ii) of Income Tax (1961) for the purpose of receiving donations/financial assistance for research / research project; The Sponsor(s) /donor(s) can claim exemption from the payment of Income Tax to the extent of 100% of the amount so contributed.


Research Achievements

1] The research and development activities in Chemistry were mainly devoted to the use of supercritical fluid carbon dioxide as a mobile phase in chromatography. As many as 100 drugs in bulk and pharmaceutical dosage forms were analysed, isocratically and simultaneously in many cases. The method was also utilised in preparative scale separation of impurities in several drugs, showing thereby the feasibility of the application of this method for the purification of drugs as well as obtainment of very expensive impurities. The impurity profiles of several drugs were obtained using this method, resulting in speed, lesser cost and more flexibility in method development. The use of solvents, toxic in most cases, was reduced by 50% by this method.
2] The activities also included investigations to find a lesser toxic organic solvent for use in mobile phase in HPLC, as reported last year. More work involving the physiochemical characteristics of the compound, CBP-1, was performed with respect to miscibility with other solvents, phase diagrams with other solvents, absorption characteristics etc.; this solvent has been found to be a substitute for acetonitrile as a mobile phase component in HPLC.
3] A novel method to assess antimicrobial activity of volatitle compounds found in herbal extracts was developed and published in the Indian Journal of Experimental Biology. In addition to screening voltatile oils for microbial activity, this method also allows quantitation of results.
4] A new bacitracin sensitive mutant of Staphylococcus aureus has been selectively isolated and deposited in microbial type culture collection (MTCC) at Indian Institute of Microbial Technology (IMTECH), Chandigad. This strain is being routinely used in our laboratory for bacitracin bioassay.
5] a) Patent for extraction Azadirachtin from neem using SFE has been sealed . (Copy enclosed) b) Patent for “a composition for curing and/or alleviating inflammation, method of preparing said composition and a method of curing and/or alleviating inflammation using said composition” has been filed with authorities, details enclosed.
6] Several papers have been published in world renowed journals for chromatography such as Talanta, Journal of Pharmaceutical and Biomedical analysis, Analytica Clinica Acta, the Analyst, Fresemius Journal of Analytical Chemistry, Analytical Letters, Journal of Chromatography, etc. Sample papers enclosed.
7] 1 Student has been awarded M. Sc. (by research) and 8 Students have been awarded Ph.D. degree by the University of Mumbai.
8] Research awards received by Dr. I. C. Bhoir, Scientific Officer at the Research Centre.

1) IDMA Research Award – 1998 for the best research paper in discipline of Pharmaceutical Analysis.

2) IDMA PAC 2000 Young Outstanding Analyst Award.

3) IDMA Research Award 2001 for the best Research paper in the discipline of Pharmaceutical Analysis.

4) DAE Young Scientist Research Award 2000 for the Research Project Solid Fluid Extraction of metals using Supercritical Carbon Dioxide.